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2023年双十一大促活动来袭！超多惊喜！点击参与~
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生物医药全球启航，百普赛斯ACROBiosystems邀您同行~
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2023年双十一大促活动来袭！超多惊喜！点击参与~
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生物医药全球启航，百普赛斯ACROBiosystems邀您同行~
MHC-多肽复合物定制服务
背景
更多信息点击下载MHC资料册
MHC（Major Histocompatibility Complex）主要组织相容性复合体，在人类中也称为 HLA，是在体内有核细胞上表达的一组多样化的细胞表面受体。它在适应性免疫应答中发挥着重要调节作用。在体内，MHC I 可以与抗原肽片段结合形成MHC I-抗原肽复合物，被T细胞受体（T cell receptor ,TCR）识别，并将其呈现于细胞表面，供T细胞识别并促发免疫应答反应。MHC I-抗原肽复合物与TCR的高度特异性结合，对适应性免疫至关重要。因此，研究MHC I-多肽复合物与TCR之间的深层关系，对于药物开发具有重要意义。为更好支持MHC相关研究，ACROBiosystems依托成熟的蛋白天然结构设计平台和真核蛋白表达技术平台，从根本上避免原核复性工艺不稳定、复合物构象不正确等问题，同时采用重链轻链共表达策略，成功开发了一系列经流式细胞验证的高生物活性天然结构MHC-复合物，包括NY-ESO-1，WT-1，GP100，GPC3等多个靶点，覆盖单体、四聚体以及多种荧光标记类型。另外，为满足客户多样化需求，我们提供多种天然构象MHC-肽复合物的定制开发服务，您可根据具体需求，向我们提出定制申请。点击定制
产品优势
真核表达系统，动物细胞内正确折叠，避免体外复性重折叠可提供FITC/PE/APC/Alexa Fluor/Biotin等多种标记类型单体/四聚体可供选择异源二聚体共表达，更接近天然构象，可被W6/32抗体正确识别全面的生物活性验证方法：SPR/ELISA/FACS等专业的MHC-多肽复合物开发平台MHC-多肽复合物 Tetramer组装示意图单体表达：在HEK293中表达生物素标记的MHC class I heavy chain 和 β2-microglobulin（β2m）复合物，经体外纯化得到生物素化的MHC class I单体骨架；多肽孵育：单体骨架与抗原多肽片段孵育得到单体MHC class I/多肽复合物；四聚体组装：单体MHC class I/多肽复合物与荧光标记链霉亲和素结合组装，最终形成四聚体，从而完成MHC Tetramer的制备；
热门定制产品列表MHC Allele Target HLA-A*0101 HLA-A*0201 HLA-A*0301 HLA-A*1101 HLA-A*2402 HLA-A*30:01 HLA-A*3303 HLA-B*1501 HLA-B*1525 HLA-B*3802 HLA-B*4601 HLA-B*0702 HLA-C*0102HLA-C*0303HLA-C*07:02:01HLA-DQA1*03:02&DQB1*03:03…… NY-ESO-1 GP100 MSLN AFP WT-1 MAGE HPV HBV HIV EBVRYRCMVRHAMM-R3Glycipan 3KRAS EW HER2 P53 PRAME PSMA …… 
点击定制
验证数据高生物活性
经流式细胞水平验证，ACROBiosystems开发的PE荧光标记HLA-A*02:01&B2M&NY-ESO-1四聚体产品，可高特异与Anti-NY-ESO-1 TCR细胞结合。
5e5 of anti-NY-ESO-1 TCR-293 cells were stained with 100 μL of 1:25 dilution (4 μL stock solution in 100 μL FACS buffer) of PE-Labeled Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein (Cat. No. HL1-HP2E5) and negative control protein respectively. PE signal was used to evaluate the binding activity (QC tested).
申请 Protocol
5e5 of anti-NY-ESO-1 TCR-293 cells were stained with 100 μL of 1:25 dilution (4 μL stock solution in 100 μL FACS buffer) of PE-Labeled Human HLA-A0201&B2M&NY-ESO-1 (SLLMWITQV) Tetramer Protein (Cat. No. HL1-HP2E6) and negative control protein respectively. PE signal was used to evaluate the binding activity (QC tested).
申请 Protocol
流式验证下，ACROBiosystems PE-labeled Human HLA-A*02:01&B2M&NY-ESO-1 Tetramer的检测信号远远高于竞品M。
Performance of PE-labeled Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer from ACROBiosystems (Cat. No. HL1-HP2E5) and other brand were evaluated by flow cytometry under the manufacturer’s recommended conditions. ACROBiosystems’ PE-Labeled NY-ESO-1 Tetramer Protein shows 3x higher MFI signal strength than competitor M, revealing much better TCR binding.
点击咨询 
Performance of PE-labeled Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Tetramer from ACROBiosystems (Cat. No. HL1-HP2E6) and other brand were evaluated by flow cytometry under the manufacturer’s recommended conditions. ACROBiosystems’ PE-Labeled NY-ESO-1 Tetramer Protein shows 2x higher MFI signal strength than competitor M, revealing much better TCR binding.
点击咨询 Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) MHC Complex可被NY-ESO-1复合物特异性抗体和HLA骨架抗体（W6/32）识别，充分证明MHC-抗原复合物具有正确的天然蛋白结构，且经严格的批次质量控制，确保产品批间一致性。
Immobilized Biotinylated Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Complex Protein (Cat. No. HL1-H82E6) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Anti-NY-ESO-1 Antibody, Human IgG1 with a linear range of 0.1-8 ng/mL (QC tested).
申请 Protocol
Immobilized Biotinylated Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Complex Protein (Cat. No. HL1-H82E6) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Anti-HLA class I Antibody, Human IgG1 (W6/32) with a linear range of 0.1-1 ng/mL (Routinely tested).
申请 Protocol
经SPR验证，HLA骨架抗体（W6/32）可与HLA亚型蛋白复合物特异性结合，亲和力良好。
Anti-HLA class I Antibody, Human IgG1 (W6/32) captured on Protein A Chip can bind Human HLA-A*11:01&B2M&KRASG12D (VVGADGVGK) Complex Protein (Cat. No. HLD-H52H4) with an affinity constant of 1.06 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).
申请 Protocol
高纯度和高稳定性
MHC-多肽复合物分别在37℃加速48h和冻融3次后，仍然具有良好的生物活性，具有高稳定性。相关推荐产品分子 货号 种属 产品描述 订购/预购 HLA-A*0201 & B2M HLM-H82Em Human Human HLA-A*02:01&B2M Tetramer Protein (Peptide free, MALS verified) HLM-HP2H3 Human PE-Labeled Human HLA-A*02:01&B2M Tetramer Protein (Peptide free) HLA-A*0201 | B2M HLM-H52H5 Human Unconjugated Human HLA-A*02:01&B2M Complex Protein (Peptide free, MALS verified) HLA-A*0301 & B2M HLM-H82W6 Human Biotinylated Human HLA-A*03:01&B2M Complex Protein (Peptide free, MALS verified) HLA-A*1101 & B2M HLM-H52H7 Human Unconjugated Human HLA-A*11:01&B2M Complex Protein (Peptide free, MALS verified) HLA-A*2402 & B2M HLM-H82W4 Human Biotinylated Human HLA-A*24:02&B2M Complex Protein (Peptide free, MALS verified) HLA-A*3303 | B2M HLM-H82W7 Human Biotinylated Human HLA-A*33:03&B2M Complex Protein (Peptide free) HLA-B*0702 & B2M HLM-H82Ek Human Biotinylated Human HLA-B*07:02&B2M Complex Protein (Peptide free, MALS verified) HLA-B*0801 & B2M HLM-H82En Human Biotinylated Human HLA-B*08:01&B2M Complex Protein (Peptide free, MALS verified) HLA-B*1501 & B2M HLM-H82W8 Human Biotinylated Human HLA-B*15:01&B2M Complex Protein (Peptide free, MALS verified) HLA-C*0303 | B2M HLM-H82E9 Human Biotinylated Human HLA-C*03:03&B2M Complex Protein (Peptide free, MALS verified) HLA-A*02:01 & B2M HLM-H82W3 Human Biotinylated Human HLA-A*02:01&B2M Complex Protein (Peptide free, MALS verified) HLA-A*11:01 & B2M HLM-H82W5 Human Biotinylated Human HLA-A*11:01&B2M Complex Protein (Peptide free, MALS verified) HLA-C*070201 & B2M HLM-H82Ed Human Biotinylated Human HLA-C*07:02:01&B2M Complex Protein (Peptide free, MALS verified) HLA-A*0201 | B2M | EW HLE-H82E4 Human Biotinylated Human HLA-A*02:01&B2M&EW (QLQNPSYDK) Complex Protein (Monomer, MALS verified) HLA-A*0201 | B2M | AFP HLA-H82E3 Human Biotinylated Human HLA-A*02:01&B2M&AFP (FMNKFIYEI) Complex Protein (Monomer, MALS verified) HLA-A*0201 | B2M | HBV HLT-H82E7 Human Biotinylated Human HLA-A*02:01&B2M&HBV (FLLTKILTI) Complex Protein (Monomer, MALS verified) HLT-H82E9 Human Biotinylated Human HLA-A*02:01&B2M&HBV (FLLTRILTI) Complex Protein (Monomer, MALS verified) HLA-A*02:01 & B2M & WT-1 HLW-H82E5 Human Biotinylated Human HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Complex Protein (Monomer, MALS verified) HLW-H52E6 Human Human HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Tetramer Protein (MALS verified) HLA-A*02:01 & B2M & gp100 HLG-H82E6 Human Biotinylated Human HLA-A*02:01&B2M&gp100 (YLEPGPVTA) Complex Protein (Monomer, MALS verified) HLA-A*0201 | B2M & HIV Gag HLH-H82E8 Human Biotinylated Human HLA-A*02:01&B2M&HIV Gag (SLYNTVATL) Complex Protein (Monomer, MALS verified) HLA-A*0201 | B2M | MAGE-A1 HLM-H82E1 Human Biotinylated Human HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Complex Protein (Monomer, MALS verified) HLA-A*0201 | B2M | MAGE-A2 HLM-H82E6 Human Biotinylated Human HLA-A*02:01&B2M&MAGE-A2 (YLQLVFGIEV) Complex Protein (Monomer, MALS verified) HLA-A*0201 | B2M | MAGE-A3 HLM-H82E3 Human Biotinylated Human HLA-A*02:01&B2M&MAGE-A3 (KVAELVHFL) Complex Protein (Monomer, MALS verified) HLA-A*0201 | B2M | MAGE-A4 HLM-H82E5 Human Biotinylated Human HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Complex Protein (Monomer, MALS verified) HLM-H52H6 Human Unconjugated Human HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Complex Protein (Monomer, MALS verified) HLA-C*07:02:01 & B2M & RYR HLR-H52W2 Human Biotinylated Human HLA-C*07:02:01&B2M&RYR (RYRPGTVAL) Complex Protein (Monomer) HLA-A*0201 & B2M & CMV pp65 HLC-H82E5 Human Biotinylated Human HLA-A*02:01&B2M&CMV pp65 (NLVPMVATV) Complex Protein (Monomer, MALS verified) HLA-A*0201 & B2M & HPV16-E7 HL7-H82E5 Human Biotinylated Human HLA-A*02:01&B2M&HPV16-E7 (YMLDLQPET) Complex Protein (Monomer, MALS verified) HLA-A*0201 | B2M | HPV16-E6 HLH-HP2H7 Human PE-Labeled Human HLA-A*02:01&B2M&HPV16-E6 (TIHDIILECV) Tetramer Protein HLA-A*0201 | B2M | HPV16-E7 HL7-HP2H7 Human PE-Labeled Human HLA-A*02:01&B2M&HPV16-E7 (YMLDLQPET) Tetramer Protein HLA-A*0201 | B2M | NY-ESO-1 HL1-HP2E5 Human PE-Labeled Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein HL1-HP2E6 Human PE-Labeled Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Tetramer Protein HLA-A*0201 | B2M | RHAMM-R3 HLR-H82E6 Human Biotinylated Human HLA-A*02:01&B2M&RHAMM-R3 (ILSLELMKL) Complex Protein (Monomer, MALS verified) HLA-A*02:01 & B2M & NY-ESO-1 HL1-H82E4 Human Biotinylated Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Complex Protein (Monomer, MALS verified) HL1-H82E6 Human Biotinylated Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Complex Protein (Monomer, MALS verified) HL1-H52E7 Human Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Tetramer Protein (MALS verified) HL1-H52E8 Human Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein (MALS & SPR verified) HLA-A*02:01 & B2M & Glypican 3 HLG-H82E4 Human Biotinylated Human HLA-A*02:01&B2M&Glypican 3 (FVGEFFTDV) Complex Protein (Monomer, MALS verified) HLG-H52E5 Human Human HLA-A*02:01&B2M&Glypican 3 (FVGEFFTDV) Tetramer Protein (MALS verified) HLA-A*0201 & B2M & AFP (FMNKFIYEI) HLA-HP2H5 Human PE-Labeled Human HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein HLA-A*0201 & B2M & p53 (HMTEVVRHC) HLP-H82E3 Human Biotinylated Human HLA-A*02:01&B2M&p53 (HMTEVVRHC) Complex Protein (Monomer, MALS verified) HLP-HP2H6 Human PE-Labeled Human HLA-A*02:01&B2M&p53 (HMTEVVRHC) Tetramer Protein HLA-A*0201 & B2M & p53 (HMTEVVRRC) HLP-H82E4 Human Biotinylated Human HLA-A*02:01&B2M&p53 (HMTEVVRRC) Complex Protein (Monomer, MALS verified) HLP-H52H5 Human Human HLA-A*02:01&B2M&p53 (HMTEVVRRC) Tetramer Protein (MALS verified) HLA-A*0201 & B2M & PAP (ALDVYNGLL) HLP-HP2Hb Human PE-Labeled Human HLA-A*02:01&B2M&PAP (ALDVYNGLL) Tetramer Protein HLA-A*0201 | B2M | p53 (RMPEAAPPV) HLP-H82E8 Human Biotinylated Human HLA-A*02:01&B2M&p53 (RMPEAAPPV) Complex Protein (Monomer, MALS verified) HLA-A*0201 & B2M & HER2 (KIFGSLAFL) HL2-H82E5 Human Biotinylated Human HLA-A*02:01&B2M&HER2 (KIFGSLAFL) Complex Protein (Monomer, MALS verified) HLA-A*0201 & B2M & PSMA (MMNDQLMFL) HLA-H82E6 Human Biotinylated Human HLA-A*02:01&B2M&PSMA (MMNDQLMFL) Complex Protein (Monomer, MALS verified) HLA-A*0301 & B2M & KRAS (VVGAGGVGK) HLS-H82E5 Human Biotinylated Human HLA-A*03:01&B2M&KRAS (VVGAGGVGK) Complex Protein (Monomer, MALS verified) HLS-H52H4 Human Human HLA-A*03:01&B2M&KRAS (VVGAGGVGK) Complex Protein (Monomer, MALS verified) HLA-A*1101 & B2M & EBV (AVFDRKSDAK) HLE-H82E5 Human Biotinylated Human HLA-A*11:01&B2M&EBV (AVFDRKSDAK) Complex Protein (Monomer, MALS verified) HLA-A*1101 | B2M | KRAS (VVGAGGVGK) HLS-H82E3 Human Biotinylated Human HLA-A*11:01&B2M&KRAS (VVGAGGVGK) Complex Protein (Monomer, MALS verified) HLS-H52H5 Human Human HLA-A*11:01&B2M&KRAS (VVGAGGVGK) Complex Protein (Monomer, MALS verified) HLS-HA2H9 Human Alexa Fluor? 647-Labeled Human HLA-A*11:01&B2M&KRAS (VVGAGGVGK) Complex ProteinStar Staining (Monomer) HLA-A*2402 & B2M & p53 (TYSPALNKMF) HLP-H82Eb Human Biotinylated Human HLA-A*24:02&B2M&p53 (TYSPALNKMF) Complex Protein (Monomer, MALS verified) HLP-HP2Hc Human PE-Labeled Human HLA-A*24:02&B2M&p53 (TYSPALNKMF) Tetramer Protein HLA-A*2402 & B2M & WT-1 (CYTWNQMNL) HLW-H82E6 Human Biotinylated Human HLA-A*24:02&B2M&WT-1 (CYTWNQMNL) Complex Protein (Monomer, MALS verified) HLA-A*3303 & B2M & EGF R(HVKITDFGR) HLR-H82E3 Human Biotinylated Human HLA-A*33:03&B2M&EGF R (HVKITDFGR) Complex Protein (Monomer, MALS verified) HLA-A*0201 & B2M & HER2 (LIAHNQVRQV) HL2-H82E3 Human Biotinylated Human HLA-A*02:01&B2M&HER2 (LIAHNQVRQV) Complex Protein (Monomer, MALS verified) HLA-A*0201 & B2M & KRAS (KLVVVGAGGV) HLS-H82E4 Human Biotinylated Human HLA-A*02:01&B2M&KRAS (KLVVVGAGGV) Complex Protein (Monomer, MALS verified) HLA-A*0201 | B2M | p53 (GLAPPQHLIRV) HLP-H82E2 Human Biotinylated Human HLA-A*02:01&B2M&p53 (GLAPPQHLIRV) Complex Protein (Monomer, MALS verified) HLA-A*0301 & B2M & gp100 (ALLAVGATK) HLG-H82E3 Human Biotinylated Human HLA-A*03:01&B2M&gp100 (ALLAVGATK) Complex Protein (Monomer, MALS verified) HLA-A*0301 & B2M & KRAS (VVVGAGGVGK) HLS-H82E2 Human Biotinylated Human HLA-A*03:01&B2M&KRAS (VVVGAGGVGK) Complex Protein (Monomer, MALS verified) HLS-H52H6 Human Human HLA-A*03:01&B2M&KRAS (VVVGAGGVGK) Complex Protein (Monomer, MALS verified) HLA-A*1101 & B2M & KRAS (VVVGAGGVGK) HLS-H82E6 Human Biotinylated Human HLA-A*11:01&B2M&KRAS (VVVGAGGVGK) Complex Protein (Monomer, MALS verified) HLS-H52E7 Human Unconjugated Human HLA-A*11:01&B2M&KRAS (VVVGAGGVGK) Complex Protein (Monomer, MALS verified) HLS-HA2H8 Human Alexa Fluor? 647-Labeled Human HLA-A*11:01&B2M&KRAS (VVVGAGGVGK) Complex ProteinStar Staining (Monomer) HLA-A*0201 & B2M & HIV Gag (SLYNTVATL) HLH-HP2H6 Human PE-Labeled Human HLA-A*02:01&B2M&HIV Gag (SLYNTVATL) Tetramer Protein HLA-A*0201 | B2M & MAGE-A4 (KVLEHVVRV) HLP-H82E5 Human Biotinylated Human HLA-A*02:01&B2M&MAGE-A4 (KVLEHVVRV) Complex Protein (Monomer, MALS verified) HLA-A*0201 | B2M | MAGE-A4 (KVLEHVVRV) HLP-HP2H3 Human PE-Labeled Human HLA-A*02:01&B2M&MAGE-A4 (KVLEHVVRV) Tetramer Protein HLA-A*0201 & B2M & MAGE-A10 (GLYDGMEHL) HLM-H82Ec Human Biotinylated Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Complex Protein (Monomer, MALS verified) HLA-A*0201 & B2M & NY-ESO-1 (SLLMWITQV) HL1-H82T3 Human Biotinylated Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Complex Protein (Monomer, MALS verified) HL1-H52C6 Human Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Tetramer Protein (MALS verified) HL1-HA2H8 Human APC-Labeled Human HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Tetramer Protein HLA-A*02:01 & B2M & MAGE-A4 (KVLEHVVRV) HLK-H52E5 Human Human HLA-A*02:01&B2M&MAGE-A4 (KVLEHVVRV) Tetramer Protein (MALS verified) HLA-A*0301 & B2M & KRASG12C (VVGACGVGK) HLC-H82E6 Human Biotinylated Human HLA-A*03:01&B2M&KRASG12C (VVGACGVGK) Complex Protein (Monomer, MALS verified) HLC-H52H4 Human Human HLA-A*03:01&B2M&KRASG12C (VVGACGVGK) Complex Protein (Monomer, MALS verified) HLA-A*1101 & B2M & HPV16-E6 (TTLEQQYNK) HLH-HP2H4 Human PE-Labeled Human HLA-A*11:01&B2M&HPV16-E6 (TTLEQQYNK) Tetramer Protein HLA-A*1101 & B2M & HPV16-E7 (IVCPICSQK) HL7-HP2H4 Human PE-Labeled Human HLA-A*11:01&B2M&HPV16-E7 (IVCPICSQK) Tetramer Protein HLA-A*1101 | B2M | KRASG12D (VVGADGVGK) HLD-H82E5 Human Biotinylated Human HLA-A*11:01&B2M&KRASG12D (VVGADGVGK) Complex Protein (Monomer, MALS verified) HLD-H52H4 Human Human HLA-A*11:01&B2M&KRASG12D (VVGADGVGK) Complex Protein (Monomer, MALS verified) HLD-H52H8 Human Human HLA-A*11:01&B2M&KRASG12D (VVGADGVGK) Tetramer Protein HLD-HA2H7 Human Alexa Fluor? 488-Labeled Human HLA-A*11:01&B2M&KRASG12D (VVGADGVGK) Complex ProteinStar Staining (Monomer) HLA-A*1101 | B2M | KRASG12V (VVGAVGVGK) HLV-H82E6 Human Biotinylated Human HLA-A*11:01&B2M&KRASG12V (VVGAVGVGK) Complex Protein (Monomer, MALS verified) HLV-H52H3 Human Human HLA-A*11:01&B2M&KRASG12V (VVGAVGVGK) Complex Protein (Monomer, MALS verified) HLV-H52H8 Human Human HLA-A*11:01&B2M&KRASG12V (VVGAVGVGK) Tetramer Protein HLA-A*2402 & B2M & NY-ESO-1 (LLMWITQCF) HL1-H82E3 Human Biotinylated Human HLA-A*24:02&B2M&NY-ESO-1 (LLMWITQCF) Complex Protein (Monomer, MALS verified) HLA-A*3001 & B2M & KRASG12V (VVGAVGVGK) HLV-HA2H7 Human APC-Labeled Human HLA-A*30:01&B2M&KRASG12V (VVGAVGVGK) Tetramer Protein HLA-B*0702 & B2M & HPV16 E7 (KPTLKEYVL) HL7-H82E4 Human Biotinylated Human HLA-B*07:02&B2M&HPV16 E7 (KPTLKEYVL) Complex Protein (Monomer, MALS verified) HLA-A*0201 & B2M & KRASG12C (KLVVVGACGV) HLC-H82E9 Human Biotinylated Human HLA-A*02:01&B2M&KRASG12C (KLVVVGACGV) Complex Protein (Monomer, MALS verified) HLA-A*0201 & B2M & KRASG12D (KLVVVGADGV) HLD-H82E4 Human Biotinylated Human HLA-A*02:01&B2M&KRASG12D (KLVVVGADGV) Complex Protein (Monomer, MALS verified) HLA-A*0201 & B2M & KRASG12V (KLVVVGAVGV) HLV-H82E3 Human Biotinylated Human HLA-A*02:01&B2M&KRASG12V (KLVVVGAVGV) Complex Protein (Monomer, MALS verified) HLV-HP2H6 Human PE-Labeled Human HLA-A*02:01&B2M&KRASG12V (KLVVVGAVGV) Tetramer Protein HLA-A*0201 & B2M & KRASG12V (VVVGAVGVGK) HLV-H82E4 Human Biotinylated Human HLA-A*02:01&B2M&KRASG12V (VVVGAVGVGK) Complex Protein (Monomer, MALS verified) HLA-A*0301 & B2M & KRASG12C (VVVGACGVGK) HLC-H82E3 Human Biotinylated Human HLA-A*03:01&B2M&KRASG12C (VVVGACGVGK) Complex Protein (Monomer, MALS verified) HLC-H52H5 Human Human HLA-A*03:01&B2M&KRASG12C (VVVGACGVGK) Complex Protein (Monomer, MALS verified) HLC-H52H9 Human Human HLA-A*03:01&B2M&KRASG12C (VVVGACGVGK) Tetramer Protein HLA-A*0301 & B2M & KRASG12D (VVVGADGVGK) HLD-H82E3 Human Biotinylated Human HLA-A*03:01&B2M&KRASG12D (VVVGADGVGK) Complex Protein (Monomer, MALS verified) HLA-A*1101 & B2M & KRASG12C (VVVGACGVGK) HLC-H82E7 Human Biotinylated Human HLA-A*11:01&B2M&KRASG12C (VVVGACGVGK) Complex Protein (Monomer, MALS verified) HLA-A*1101 & B2M & KRASG12D (VVVGADGVGK) HLD-H82E9 Human Biotinylated Human HLA-A*11:01&B2M&KRASG12D (VVVGADGVGK) Complex Protein (Monomer, MALS verified) HLD-H52E6 Human Unconjugated Human HLA-A*11:01&B2M&KRASG12D (VVVGADGVGK) Complex Protein (Monomer, MALS verified) HLD-H52H7 Human Human HLA-A*11:01&B2M&KRASG12D (VVVGADGVGK) Tetramer Protein HLD-HA2H4 Human Alexa Fluor? 488-Labeled Human HLA-A*11:01&B2M&KRASG12D (VVVGADGVGK) Complex ProteinStar Staining (Monomer) HLA-A*1101 & B2M & KRASG12V (VVVGAVGVGK) HLV-H82E7 Human Biotinylated Human HLA-A*11:01&B2M&KRASG12V (VVVGAVGVGK) Complex Protein (Monomer, MALS verified) HLV-H52E5 Human Unconjugated Human HLA-A*11:01&B2M&KRASG12V (VVVGAVGVGK) Complex Protein (Monomer, MALS verified) HLV-H52H9 Human Human HLA-A*11:01&B2M&KRASG12V (VVVGAVGVGK) Tetramer Protein 更多相关产品
参考文献:
1.Thomas C, Tampé R. MHC I assembly and peptide editing - chaperones, clients, and molecular plasticity in immunity. Curr Opin Immunol. 2021 Jun;70:48-56. doi: 10.1016/j.coi.2021.02.004. Epub 2021 Mar 6. PMID: 33689959.
2.Becar M, Kasi A. Physiology, MHC Class I. 2021 Sep 28. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–. PMID: 32310482.
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